ANDREA DE MARTINO
CNR Principal Investigator (on leave)
Politecnico di Torino & IIGM
Office / Email
Research
- Statistical mechanics, mathematical models
- Molecular networks
- Population dynamics
- Physics/biology interface
- Information processing in living systems
- Emergence of multi-cellular and population-level behaviour
Papers (selected, recent, most recent first, with links to full text and/or preprint)
- Book chapter/Review Metabolic diversity in cell populations: probability densities over the flux polytope (with M Rivas Astroza)
- Optimal metabolic strategies for microbial growth in stationary random environments (with AP Muntoni)
- Book chapter/Review Statistical-physics approaches to RNA molecules, families and networks (with S Cocco, A Pagnani, M Weigt)
- Probing single-cell fermentation fluxes and exchange networks via pH-sensing hybrid nanofibers (with V Onesto, S Forciniti, F Alemanno, K Narayanankutty, A Chandra, S Prasad, A Azzariti, G Gigli, A Barra, D De Martino, LL del Mercato)
- Relationship between fitness and heterogeneity in exponentially growing microbial populations (with AP Muntoni, A Braunstein, A Pagnani, D De Martino)
- Path-integral solution of MacArthur's resource-competition model for large ecosystems with random species-resources couplings (with AR Batista-Tomas, R Mulet)
- Initial cell density encodes proliferative potential in cancer cell populations (with C Enrico Bena, M Del Giudice, A Grob, T Gueudre, M Miotto, D Gialama, M Osella, E Turco, F Ceroni, C Bosia)
- MicroRNAs organize intrinsic variation into stem cell states (with M Chakraborty, S Hu, E Visness, M Del Giudice, C Bosia, PA Sharp, S Garg)
- Competing endogenous RNA crosstalk at system level (with M Miotto, E Marinari)
- A yield-cost tradeoff governs Escherichia coli's decision between fermentation and respiration in carbon-limited growth (with M Mori, E Marinari)
- Book chapter/Review Kinetic modelling of competition and depletion of shared miRNAs by competing endogenous RNAs [arXiv] (with A Martirosyan, M Del Giudice, C Enrico Bena, A Pagnani, C Bosia)
- Exploration-exploitation tradeoffs dictate the optimal distributions of phenotypes for populations subject to fitness fluctuations [arXiv] (with M Miotto, T Gueudre)
- Statistics of optimal information flow in ensembles of regulatory motifs [arXiv] (with J Fiorentino, A Crisanti)
- Review An introduction to the maximum entropy approach and its application to inference problems in biology (with D De Martino)
- Quantifying the entropic cost of cellular growth control [arXiv] (with D De Martino, F Capuani)
- Translating ceRNA susceptibilities into correlation functions [bioRXiv] (with A Martirosyan, M Marsili)
- Microenvironmental cooperation promotes early spread and bistability of a Warburg-like phenotype (with J Fernandez-de-Cossio-Diaz, R Mulet)
- Constrained Allocation Flux Balance Analysis (with M Mori, T Hwa, OC Martin, E Marinari)
- Growth against entropy in bacterial metabolism: the phenotypic trade-off behind empirical growth rate distributions in Escherichia coli [arXiv] (with D De Martino, F Capuani)
- Probing the limits to microRNA-mediated control of gene expression (with A Martirosyan, M Figliuzzi, E Marinari)
- Inferring metabolic phenotypes from the exometabolome through a thermodynamic variational principle [arXiv] (with D De Martino, F Capuani)
- RNA-Based Regulation: Dynamics and Response to Perturbations of Competing RNAs (with M Figliuzzi, E Marinari)
- Identifying All Moiety Conservation Laws in Genome-Scale Metabolic Networks (with D De Martino, R Mulet, A Pagnani)
- Boolean constraint satisfaction problems for reaction networks [arXiv] (with A Seganti, F Ricci Tersenghi)
- MicroRNAs as a selective channel of communication between competing RNAs: a steady state theory (with M Figliuzzi, E Marinari)
- An older review article covering my work on games, interacting agents and all that:
- Review Statistical mechanics of socio-economic systems with heterogeneous agents [arXiv] (with M Marsili)
Teaching
- 2021-23 : Elettromagnetismo (Politecnico di Torino)
- 2011-16 : Biofisica Teorica (Sapienza Univ di Roma)
- 2010-11 : Fisica Statistica dei Sistemi Biologici (Sapienza Univ di Roma)
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